Background: Chronic kidney disease (CKD) is a common and growing problem worldwide; Earlier recognition of chronic kidney disease (CKD) could slow progression, prevent complications, and reduce cardiovascular-related outcomes. Study objective: to show the knowledge of the population Hail region on CKD and its causes, risk factors, appropriate treatment, and consequences. Methods: A cross sectional study carried out in Hail region during the period from 1 October to 31 December. Data was collected by personal interview using a predesigned questionnaire containing all the relevant questions. Results: Majority (60%) of participant have a good knowledge about CKD, 678 (71.4%) of participant think that alcohol drinking are the most cause of CKD, 81.2% think smoking, 62.7% think DM and 60.7% think that hypertension is the cause. Side pain are the most (84.4%) known symptom of CKD followed by difficulty urination known in 74.4%, Oliguria in 67.8% and hypertension in 34.4%. About the risk factors of the disease, 96.6% think that some food was the risk factors of CKD, 89.8% think about obesity, 81.5% think about Analgesic, 56.0% think about DM and 30.5% think about positive family history of CKD. It's found also that 85.6% of participant know that CKD 85.6% can't be treated without renal transplantation, 83.3% with dialysis and 71.2% by drugs also large number of them know that it can be treated in high percentage. Almost all of them say that CKD can be decreased by performing muscular exercises. Conclusion: Current estimates of CKD awareness indicate that awareness remains unsatisfactory. Also, little is known regarding whether increased awareness improves clinical outcomes for CKD patients. Further research is necessary to continue to design and refine awareness campaigns aimed at dissemination of basic CKD information, given both the high prevalence of CKD and its risk factors and the low estimated awareness of CKD.