ManageChatDiscover
95679

Immunological And Biochemical Changes In Draft Horses Naturally Infested With Gastrointestinal Nematodes With Trail Of Treatment With Fenbendazole In Sharkia Governorate

Article

Last updated: 03 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Academic and Pre-clinical Veterinary Sciences (Physiology, Histology, …rology, Parasitology, Pharmacology, Forensic Medicine and Toxicology)

Abstract

This study is done to clarify some adverse effects of gastrointestinal nematodes on immunological and biochemical status of draft horses and modulating by fenbendazol. Parasitological examination of 50 faecal samples revealed presence of gastrointestinal  nematodes  eggs in 38 (76%), horses distributed according to age {1- 4years 13 (34.21%), > 4-10 years 10 (26.32%)}, the type of infestations were  single 12(31.58 %) or mixed 26 (68.42%). The single infestation were Strongylus spp < /em> 6 (15.79 %), Parascaris equorum, 4 (10.53 %), Oxyuris equorum 2(5.26%) while mixed infestation were Strongylus spp with Parascaris equorum 7 (18.42%), Parascaris equorum with Oxyuris equorum 5(13.16 %) and Strongylus spp with Parascaris equorum with Oxyuris equorum 14 (36.84%)}. The treatment with Fenbendazole revealed 100% reduction in egg count/gm on day 9 post treatment.
Gastrointestinal nematodes induce leukocytosis, neutrophilia, eosinophilia, monocytosis insignificant rise in lymphocytes, γ, β, total globulin beside insignificant decrease in α globulin and A/G ratio coupled with significant rise in AST, ALT, urea, creatinine and significant reduction in T.protein, albumin, ALP, trace elements (selenium, copper, iron and zinc) compared with healthy horse.
The present study revealed that fenbendazole had a non significant effect on total and differential leukocytic count and biochemical parameters in healthy draft horses.
In conclusion, the present study showed that gastrointestinal nematodes induce some adverse effects on immune status and biochemical parameters. Those effects were returned to the normal levels at 15 days post treatment with fenbendazole.

DOI

10.21608/zvjz.2013.95679

Authors

First Name

Nasr

Last Name

SS

MiddleName

-

Affiliation

Parasitology departments, Animal Health Research Institute, Zagazig Branches

Email

-

City

-

Orcid

-

First Name

Neesren A

Last Name

Shawky

MiddleName

-

Affiliation

Biochemistry departments, Animal Health Research Institute, Zagazig Branches

Email

-

City

-

Orcid

-

First Name

Aly Salah

Last Name

ABS

MiddleName

-

Affiliation

Biochemistry departments. Animal Health Research Institute, Kafer El-Sheikh Branches

Email

-

City

-

Orcid

-

First Name

Hussen

Last Name

E M

MiddleName

-

Affiliation

Biochemistry departments, Animal Health Research Institute, Zagazig Branches

Email

-

City

-

Orcid

-

Volume

41

Article Issue

2

Related Issue

14242

Issue Date

2013-06-01

Receive Date

2020-06-14

Publish Date

2013-06-01

Page Start

9

Page End

17

Print ISSN

1110-1458

Online ISSN

2357-075X

Article File

ZVJZ_Volume 41_Issue 2_Pages 9-17.pdf

PDF . 4.3MB

Link

https://zvjz.journals.ekb.eg/article_95679.html

Detail API

https://zvjz.journals.ekb.eg/service?article_code=95679

Order

2

Type

Original Article

Type Code

601

Publication Type

Journal

Publication Title

Zagazig Veterinary Journal

Publication Link

https://zvjz.journals.ekb.eg/

MainTitle

Immunological And Biochemical Changes In Draft Horses Naturally Infested With Gastrointestinal Nematodes With Trail Of Treatment With Fenbendazole In Sharkia Governorate

Details

Type

Article

Created At

22 Jan 2023