ManageChatDiscover
94456

Therapeutic Evaluation Of The Antiviral Activity Of Azadirachta indica In Comparison To Amantadine Hydrochloride Against Avian Influenza Virus Infection In Ducks

Article

Last updated: 03 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Clinical Science, Surgery and Veterinary Diseases (Pathology, Clinical…ltry Diseases, Fish Diseases and Management, Surgery, Theriogenology)

Abstract

Twelve AI isolates were isolated in ECE from diseased backyard ducks showed signs of depression, anorexia, greenish or watery diarrhea, severe neurological signs, and high mortalities. All isolates were identified using HIT to be H5. RT-PCR was used for detection and subtyping of AIVs using specific pairs of primers to amplify the hemagglutinin gene of subtype H5 and neuraminidase gene of subtype N1. Analysis of RNA extracted yielded positive reactions of correct size as H5 subtype specific primers (545 bp) and N1 subtype specific primers (616 bp). The efficacy of Azadirachta indicaagainst AIV infection was evaluated in comparison toamantadinehydrochloride in 2-wk-old balady ducks inoculated with 0.1ml×106 EID50/ml of AIV H5N1. Aqueous Neem leaves extract provided ducks with 100% protection level, whereas neither clinical signs nor mortalities were recorded, while Adamine® presented 70% only.

DOI

10.21608/zvjz.2013.94456

Authors

First Name

A M

Last Name

Hegazy

MiddleName

-

Affiliation

Avian & Rabbit Med. Dept., Faculty of Vet. Med., Zagazig Univ. Zagazig, Egypt.

Email

-

City

-

Orcid

-

First Name

M A

Last Name

El-Sisi

MiddleName

-

Affiliation

Avian & Rabbit Med. Dept., Faculty of Vet. Med., Zagazig Univ. Zagazig, Egypt.

Email

-

City

-

Orcid

-

First Name

A A

Last Name

Nazim

MiddleName

-

Affiliation

Nutrition Dep., Zagazig Univ. Hospitals, Zagazig Univ. Zagazig, Egypt.

Email

-

City

-

Orcid

-

Volume

41

Article Issue

1

Related Issue

14241

Issue Date

2013-03-01

Receive Date

2020-06-08

Publish Date

2013-03-01

Page Start

35

Page End

56

Print ISSN

1110-1458

Online ISSN

2357-075X

Article File

ZVJZ_Volume 41_Issue 1_Pages 35-56.pdf

PDF . 12.0MB

Link

https://zvjz.journals.ekb.eg/article_94456.html

Detail API

https://zvjz.journals.ekb.eg/service?article_code=94456

Order

5

Type

Original Article

Type Code

601

Publication Type

Journal

Publication Title

Zagazig Veterinary Journal

Publication Link

https://zvjz.journals.ekb.eg/

MainTitle

Therapeutic Evaluation Of The Antiviral Activity Of Azadirachta indica In Comparison To Amantadine Hydrochloride Against Avian Influenza Virus Infection In Ducks

Details

Type

Article

Created At

22 Jan 2023