This study was done in the period during 2009 to 2011 on a total number of 929 cattle in 2 Egyptian Governorates “Sharkia and Dakahlia" which were 552 Native breed and 377 imported breed, aged from one month to 9 years old. All of them were vaccinated by sheep pox vaccine.
The infected animals with LSD showed severe clinical signs which include skin nodules varied in number from one up to several hundreds, sometimes covered all the body, varied in diameter from 0.5 to 5 cm, regular in shape, rounded with flatted centers. The nodules are hard, farm and painful with erected hairs make scabs detached leaving wounds and make scars when recovery. The affected animals showed body temperature 39.5-41ºC became normal within 1-3 days, enlarged lymph nodes, oedema in one or more leg. There is a nasal and lacrimal discharge on the animals.
Our obtained results revealed that LSD affect 158 out of 552 local bread and 186 out of 377 foreign bread, the morbidity was 28.63% and 49.37% respectively. The morbidity in Sharkia was 26.93% and Dakahlia was 47.52%.
The mortality rate was very low from 0-1.5%.
PCR technique was done for accurate diagnosis of LSD that give 100% of skin samples “samples of choice".