28663

Assessment of the Duration of Maternal Antibodies Specific to Live Attenuated peste des petits Ruminant Virus Vaccine in Lambs and Kids

Article

Last updated: 03 Jan 2025

Subjects

-

Tags

Academic and Pre-clinical Veterinary Sciences (Physiology, Histology, …rology, Parasitology, Pharmacology, Forensic Medicine and Toxicology)

Abstract

Maternal immunity in lambs and kids born from vaccinated dams with peste des petits ruminant (PPR) live attenuated cell culture vaccine was evaluated by using competitive ELISA (c-ELISA). Serum samples were collected from each dam prior to the vaccination to detect the titre of antibody against the infection with PPRV and from lambs and kids on the day of birth, then every 15 days until reach 4.5 months of age to determine the level of maternal antibodies against PPR virus transferred from vaccinated dams to their newly born lambs and kids. Results showed that the antibody titer averages in lambs and kids reach the maximum at one month of age (OD average below 20) then, declined gradually at 105 days in which 80 % of kids still have OD average below 50while 40% of lambs are still protected. So, we recommended the application of vaccine to newly born lambs and kids from immunized dams at 3 months of age by live attenuated PPR vaccine strain Egypt/87 grown on the Vero cell culture.

DOI

10.21608/zvjz.2017.28663

Keywords

Small ruminants, PPRV- vaccine, maternal immunity, c-ELISA

Authors

First Name

Ayman A-

Last Name

Shehata

MiddleName

-

Affiliation

Animal Medicine Department, Division of Infectious Diseases, Faculty of Veterinary Medicine, Zagazig University, 44511, Egypt

Email

-

City

-

Orcid

-

First Name

Elshaima M.

Last Name

Fawzi

MiddleName

-

Affiliation

Animal Medicine Department, Division of Infectious Diseases, Faculty of Veterinary Medicine, Zagazig University, 44511, Egypt

Email

elshaimafawzi@yahoo.es

City

-

Orcid

-

First Name

Afaf M.

Last Name

Menaze

MiddleName

-

Affiliation

Animal Medicine Department, Division of Infectious Diseases, Faculty of Veterinary Medicine, Zagazig University, 44511, Egypt

Email

-

City

-

Orcid

-

First Name

Mohamed I.

Last Name

Essa

MiddleName

-

Affiliation

Animal Medicine Department, Division of Infectious Diseases, Faculty of Veterinary Medicine, Zagazig University, 44511, Egypt

Email

-

City

-

Orcid

-

First Name

Mervat M.

Last Name

Mahmoud

MiddleName

-

Affiliation

Virology Department, Animal Health Research Institute, Dokki, Giza, Egypt

Email

-

City

-

Orcid

-

Volume

45

Article Issue

Supplementary 1

Related Issue

5095

Issue Date

2017-10-01

Receive Date

2019-03-13

Publish Date

2017-10-01

Page Start

181

Page End

188

Print ISSN

1110-1458

Online ISSN

2357-075X

Link

https://zvjz.journals.ekb.eg/article_28663.html

Detail API

https://zvjz.journals.ekb.eg/service?article_code=28663

Order

19

Type

Original Article

Type Code

601

Publication Type

Journal

Publication Title

Zagazig Veterinary Journal

Publication Link

https://zvjz.journals.ekb.eg/

MainTitle

Assessment of the Duration of Maternal Antibodies Specific to Live Attenuated peste des petits Ruminant Virus Vaccine in Lambs and Kids

Details

Type

Article

Created At

22 Jan 2023