Beta
14387

Modeling of Biological Data Based on Regression Methods

Article

Last updated: 22 Jan 2023

Subjects

-

Tags

Academic and Pre-clinical Veterinary Sciences (Physiology, Histology, …rology, Parasitology, Pharmacology, Forensic Medicine and Toxicology)

Abstract

The ordinary least square estimates of multiple regression parameters is characterized by low bias and large variance leading to poor performance in both prediction and interpretation of the regression model under study. Penalized regression techniques represented in ridge, lasso and elastic net were used to improve the ordinary least square estimates performance. Categorical regression algorithm provides efficient procedure for computing the regression coefficients of ridge, lasso, and elastic Net models. The statistical analysis was done on ten single nucleotide polymorphisms simulated data with strong linkage disequilibrium as predictors of a continuous phenotypic trait. The coefficients were 39%, 34%, 29% and 28% for ridge, elastic net, lasso and stepwise multiple regression methods, respectively. The current study finished that ridge regression followed by elastic net regression performed better than the other regression methods.

DOI

10.21608/zvjz.2018.14387

Keywords

Ridge, Lasso, Penalization, regression, Elastic net

Authors

First Name

Khairy

Last Name

El-Bayomi

MiddleName

M.

Affiliation

Animal Wealth Development Department, Faculty of Veterinary Medicine, Zagazig University, 44511, Egypt

Email

-

City

-

Orcid

-

First Name

Elhoussainy

Last Name

Rady

MiddleName

A.

Affiliation

Applied Statistics and Econometrics Department, Institute of Statistical Studies and Research, Cairo University

Email

-

City

-

Orcid

-

First Name

Mahmoud

Last Name

El-Tarabany

MiddleName

S.

Affiliation

Animal Wealth Development Department, Faculty of Veterinary Medicine, Zagazig University, 44511, Egypt

Email

-

City

-

Orcid

-

First Name

Hala

Last Name

Mahmoud

MiddleName

I.

Affiliation

Animal Wealth Development Department, Faculty of Veterinary Medicine, Zagazig University, 44511, Egypt

Email

drhalastat@gmail.com

City

-

Orcid

-

Volume

46

Article Issue

2

Related Issue

2824

Issue Date

2018-06-01

Receive Date

2018-09-22

Publish Date

2018-06-01

Page Start

146

Page End

153

Print ISSN

1110-1458

Online ISSN

2357-075X

Link

https://zvjz.journals.ekb.eg/article_14387.html

Detail API

https://zvjz.journals.ekb.eg/service?article_code=14387

Order

7

Type

Original Article

Type Code

601

Publication Type

Journal

Publication Title

Zagazig Veterinary Journal

Publication Link

https://zvjz.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023