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Molecular Characterization, Hematological and Biochemical Studies on Foot and Mouth Disease Virus Serotype O in Buffaloes and Cows in Dakahlia Governorate, Egypt

Article

Last updated: 03 Jan 2025

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Subjects

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Tags

Clinical Science, Surgery and Veterinary Diseases (Pathology, Clinical…ltry Diseases, Fish Diseases and Management, Surgery, Theriogenology)

Abstract

The present study aimed to evaluate the hematological and serum biochemical parameters in buffaloes and cows infected with foot and mouth disease (FMD) virus. Forty buffaloes and cows (6 months - 2 years old) were used. Twenty buffaloes and cows clinically healthy and were used as control, the other twenty buffaloes and cows showed characteristic clinical signs of FMD. Blood samples were collected and serum was separated from both groups to measure the hematological and biochemical parameters. Infected buffaloes and cows showed fever, anroxia, excessive foamy salivation and ulcer formation in the mouth. Compared to the control buffaloes, erythrocytic count (RBCs), hemoglobin (Hb) and packed cell volume (PCV) in the FMD infected buffaloes were significantly decreased, while mean corpascular hemoglobin (MCH) was significantly increased. In addition, significant increase in toltal leukocyte count (TLC), neutrophils, with a significant decrease in eosinophil and lymphocyte counts were observed.Moreover, cows infected with FMD virus showed no significant changes in the erythrogram, while, significant increases in TLC and neutrophils, with a significant decrease in eosinophil and lymphocyte counts were observed when compared with the control group. There were significant decreases in the levels of serum total proteins, albumin and globulin, while serum asprtate transferase (AST), creatinine phospho-kinase (CPK), glucose and cortisol levels were significantly increased in the infected animals. Tissue and saliva specimens were collected and analyzed by using universal primer using reverse-transcription polymerase chain reaction (RT-PCR). All the identified viruses were of serotype ‘O'. It is concluded that FMDV serotype ‘O' is circulating among cows and buffaloes in the study area.

DOI

10.21608/zvjz.2017.7888

Authors

First Name

Shefaa

Last Name

El-Mandrawy

MiddleName

A.M.

Affiliation

Clinical Pathology Department, Faculty of Veterinary Medicine, Zagazig University, 44511, Egypt

Email

-

City

-

Orcid

-

First Name

Gamelat

Last Name

Farag

MiddleName

-

Affiliation

Virology Department, Faculty of Veterinary Medicine, Zagazig University, 44511, Egypt

Email

shifo_vet@yahoo.com

City

-

Orcid

-

Volume

45

Article Issue

2

Related Issue

1520

Issue Date

2017-06-01

Receive Date

2017-04-27

Publish Date

2017-06-01

Page Start

156

Page End

164

Print ISSN

1110-1458

Online ISSN

2357-075X

Article File

ZVJZ_Volume 45_Issue 2_Pages 156-164.pdf

PDF . 332.2kB

Link

https://zvjz.journals.ekb.eg/article_7888.html

Detail API

https://zvjz.journals.ekb.eg/service?article_code=7888

Order

7

Type

Original Article

Type Code

601

Publication Type

Journal

Publication Title

Zagazig Veterinary Journal

Publication Link

https://zvjz.journals.ekb.eg/

MainTitle

Molecular Characterization, Hematological and Biochemical Studies on Foot and Mouth Disease Virus Serotype O in Buffaloes and Cows in Dakahlia Governorate, Egypt

Details

Type

Article

Created At

22 Jan 2023