Earthquakes are generally considered the most dangerous factor affecting the historical
buildings. The present study is focusing on the determination of the effects of earthquake
activities on the historical site of Mekaad Radwan Compound near outskirt of old Fatimid
Cairo, the area of Bab Zwiela "Bawabat El Metwali". The analysis of the seismicity data
around the site under investigation is carried out to define the design or credible earthquake.
In order to achieve the scientific, practical works; seismotectonics, Simulation of earthquake
ground motion in the site and site response are studied. The deterministic and probabilistic
approaches were carried out showing that the credible earthquake may be located at the
same seismic zone of Cairo 1992 earthquake.