Male infertility is responsible for 35% of infertile marriages. This study is
concerned with the relative importance of endocrine factors among infertile males.
The so-called "endocrine disruptors" may harm wildlife, aquatic life, or human health
by interfering with the action of reproductive and other hormones. Other factors,
which cause infertility in the males, include alcohol, vitamin deficiencies and heavy
metals. Sixty three subjects were grouped into: fertile, primary infertile and
secondary infertile and investigated for the level of hormones in their blood sera. The
hormones studied were; testosterone, estradiol, FSH, LH, and PRL. LH showed a
significant increase, (p< 0.05) between primary infertile compared to fertile males.
Therefore, LH determination could be used in conjugation with other seminal
analysis in the diagnosis of infertility among males. It is necessary to draw a
complete reproductive hormones profile for a proper laboratory diagnosis in such
cases, including biologically active LH, FSH and PRL.