This work was performed to study the effect of crude purslane extract on some aspects
of lipid and carbohydrate metabolism in normal and streptozotocin induced diabetic
male albino rats. Twenty four male albino rats, were categorized into four equal
groups. Group (1): normal control rats, group (2): purslane treated rats in
which the rats were administrated by purslane extract in a dose of 5 gm/kg orally for
three weeks, group (3):diabetic control rats and group(4): diabetic rats
treated by purslane, in which the rats were administrated by purslane extract for
three weeks. At the end of the experiment,the rats were scarified and blood samples
were collected .The results showed significant reduction in blood levels of
triglyceride, total cholesterol, LDL–cholesterol with significant increase in blood
level of HDL–cholesterol, P<0.05, and non significant change in glucose or insulin
level in purslane treated group compared with normal control group. There were
significant reduction in blood levelof triglyceride, total cholesterol, LDL–cholesterol
with significant increase in blood levelof HDL–cholesterol, and non significant
change in insulin level compared with the significant reduction in blood glucose level
in purslane treated diabetic group compared with diabetic control group. It is
concluded that crude purslane extract has beneficial effects on lipid and
carbohydrates parameters both innormal and diabetic condition.