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35188

Lead Levels in Maternal and Newborns Blood and Hair and Their Impact on Neonatal Anthropometric Measurements

Article

Last updated: 24 Dec 2024

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Abstract

Lead is a toxicant heavy metal which cross the placenta and accumulate in the fetal
tissues. Prenatal exposure to lead poses a health threat and causes adverse effects on
intrauterine growth and neurodevelopment. The present study aimed to: 1) Determine
maternal as well as fetal blood and hair lead levels. 2) Evaluate the correlation
between maternal and fetal levels of lead. 3) Study the possible effects of maternal
blood lead levels on the anthropometric measurements of their neonates. The study
was carried out on 38 pregnant women and their fetuses. All blood and hair samples
of the mothers and their fetuses were analyzed for estimation of lead concentration
using atomic absorption Spectrophotometer. The results showed significant increase
in maternal and fetal blood as well as hair lead. There was statistically significant
correlation between maternal and fetal blood lead and maternal and fetal hair lead.
The high levels of maternal blood lead affect the anthropometric measurement of the
fetus. The affection of dimension of infant growth at level ≥ 10 μg/dl was more than
low levels. Also, there was significant negative correlation between maternal blood
lead levels and birth weight, fetal length, head circumference, chest circumference
and mid-arm circumference. In conclusion, there was highly statistically significant
relation between maternal and fetal blood lead levels, hair help in the determination
of level of lead exposure as there was significant relation between fetal blood and
hair lead levels. Also, lead levels in maternal blood affect neonatal anthropometric
measurements. Simple preventive measures may play a role in decreasing maternal
blood lead and thereby decreasing trans-placental transfer of lead to the fetus and
protect the fetus from adverse effect of lead.

DOI

10.21608/besps.2013.35188

Keywords

Lead, maternal lead, fetal lead, birth weight, Head circumference

Authors

First Name

Sahar

Last Name

El-DeeK

MiddleName

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Affiliation

Medical Biochemistry Department, Faculty of Medicine,Assiut University, Assiut, Egypt

Email

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City

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Orcid

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First Name

Zaghloul

Last Name

Mohammed

MiddleName

-

Affiliation

Forensic Medicine and Clinical Toxicology, Department, Faculty of Medicine, Assiut University, Assiut, Egypt

Email

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City

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Orcid

-

First Name

Hala

Last Name

Fathy

MiddleName

-

Affiliation

Forensic Medicine and Clinical Toxicology, Department, Faculty of Medicine, Assiut University, Assiut, Egypt

Email

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City

-

Orcid

-

First Name

Safwat

Last Name

Mohamed

MiddleName

-

Affiliation

Obstetric and Gynecology Department, Faculty of Medicine, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

Volume

33

Article Issue

1

Related Issue

5749

Issue Date

2013-06-01

Receive Date

2013-06-17

Publish Date

2013-06-01

Page Start

107

Page End

122

Print ISSN

1110-0842

Online ISSN

2356-9514

Link

https://besps.journals.ekb.eg/article_35188.html

Detail API

https://besps.journals.ekb.eg/service?article_code=35188

Order

9

Type

Original Article

Type Code

567

Publication Type

Journal

Publication Title

Bulletin of Egyptian Society for Physiological Sciences

Publication Link

https://besps.journals.ekb.eg/

MainTitle

Lead Levels in Maternal and Newborns Blood and Hair and Their Impact on Neonatal Anthropometric Measurements

Details

Type

Article

Created At

22 Jan 2023