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202483

Diagnostic and Comparative Therapeutic Study on Treatment of Gastroenteritis in Dogs Without and With Histamine H2 Receptor Antagonist

Article

Last updated: 22 Jan 2023

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Abstract

This study was applied to investigate the effect of Antodine® (Famotidine, 40 mg PO BID/~25 kg dog twice daily) supplement for 5 days in dogs suffering from gastro-enteritis. Twenty seven dogs enrolled in this study, their ages ranged between 6-8 month and their bodyweight ranged between 20-27 kg. Dogs divided into two groups, first group (Gp) included nine (n=9) clinically healthy dogs considered as control group, second group (Gp 2) included eighteen (n=18) dogs suffering from gastro-enteritis, kept in Dog Kennel and divided into two subgroups: (Gp2 A) included 9 dogs given the traditional regimen of treatment (GIT protectant, Anti-emetic, and fluid therapy); and (Gp 2 B) included 9 dogs treated with same regimen plus the addition of famotidine. Whole blood examined for changes in CBC and serum for selected biochemical constituents levels. Abdominal ultrasonography applied to detect changes in stomach and duodenum which revealed that gastritis, can produce a diffuse, mild to moderate thickening of wall with preservation of the wall layering. Early recovery and return of appetite, vital signs to normal occur at 3-5 days in dogs treated with famotidine while cases treated without famotidine recovery gained at 5-7 days of treatment.

DOI

10.21608/vmjg.2021.202483

Keywords

Dog, gastroenteritis, famotidine, hematology, Ultrasonography

Authors

First Name

Ahmed

Last Name

Wahdan

MiddleName

S

Affiliation

Department of Internal Medicine, Faculty of Veterinary Medicine, Cairo University, Egypt.

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City

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Orcid

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First Name

Taher

Last Name

Baraka

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Veterinary Medicine, Cairo University, Egypt.

Email

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City

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Orcid

-

First Name

Mohamed

Last Name

Awny

MiddleName

A

Affiliation

Department of Internal Medicine, Faculty of Veterinary Medicine, Cairo University, Egypt.

Email

-

City

-

Orcid

-

First Name

Fatma

Last Name

Tayeb

MiddleName

A

Affiliation

Department of Internal Medicine, Faculty of Veterinary Medicine, Cairo University, Egypt.

Email

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City

-

Orcid

-

Volume

67

Article Issue

1

Related Issue

23241

Issue Date

2021-12-01

Receive Date

2021-10-01

Publish Date

2021-12-01

Page Start

130

Page End

138

Print ISSN

1110-1423

Online ISSN

2537-1045

Link

https://vmjg.journals.ekb.eg/article_202483.html

Detail API

https://vmjg.journals.ekb.eg/service?article_code=202483

Order

12

Type

Original Article

Type Code

544

Publication Type

Journal

Publication Title

Veterinary Medical Journal (Giza)

Publication Link

https://vmjg.journals.ekb.eg/

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Article

Created At

22 Jan 2023