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231964

Polymeric nano sponge drug delivery system: A review

Article

Last updated: 22 Jan 2023

Subjects

-

Tags

Drug design and formulation

Abstract

Nanotechnology is redefining healthcare methods, and it is projected to have a significant impact in the next years, resulting in improved healthcare facilities. It has paved the way for therapeutic medication delivery and diagnostics.
Medical nanoparticles are materials in the nanoscale (from 1 to 100 nm) employed in the development, production, control, and use of medicinal drugs or devices employed in developing, producing, controlling, and using medicinal drugs or devices.
Aside from gene therapy, nano-based medicine delivery systems benefit cancer, diabetes, infectious diseases, neurological diseases, blood diseases, and orthopaedic-related maladies. Furthermore, the development of multifunctional nanotherapeutics is potentially needed to contribute to the present therapeutic area positively. Nanomedicines are preferable to conventional therapeutic approaches in cancer as they can transmit the drug efficiently to the damaged tissues, decreasing drug toxicity.
Nanotechnology-based medicines and diagnostics are more effective while posing little or no side effects. Micelles of polymeric paclitaxel and polymeric asparaginase conjugates have been advocated for treating several tumours in this vein.
Nanotechnology advancements have prepared nanorobotics to be applied in various healthcare applications. As a result, this review thoroughly highlights the potential of polymeric nanoparticles, Nano-emulsions, solid lipid nanoparticles, nanostructured lipid carriers, self-micellizing anticancer lipids, dendrimer, nanocapsule, and nanosponges approaches in cancer, as well as the potentialities of various nanocarriers and nanomedicines for a variety of applications in diagnostics and drug delivery.
This article reviews the most recent literature on nanotechnology, particularly cyclodextrin-based polymers, in medicinal applications.

DOI

10.21608/rpbs.2022.88495.1131

Keywords

Nanosponges, β-Cyclodextrine, Drug Delivery Systems, Solubility, nanomedicine

Authors

First Name

Shadeed

Last Name

Gad

MiddleName

-

Affiliation

Faculty of Pharmacy - Suez Canal University

Email

shaded_abdelrahman@pharm.suez.edu.eg

City

Ismailia

Orcid

0000-0001-7714-2267

First Name

Sameh

Last Name

Alhussini

MiddleName

-

Affiliation

Department of Research & Development, Alandalous for Pharmaceutical Industries, Egypt.

Email

sameh_alhussini@pharm.suez.edu.eg

City

-

Orcid

-

First Name

Ahmed

Last Name

Gardouh

MiddleName

R.

Affiliation

Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Suez Canal University.

Email

ahmed_mahmoud@pharm.suez.edu.eg

City

ismailia

Orcid

0000-0002-5387-1614

Volume

6

Article Issue

3

Related Issue

33244

Issue Date

2022-04-01

Receive Date

2022-03-15

Publish Date

2022-04-01

Page Start

34

Page End

58

Print ISSN

2536-9857

Online ISSN

2535-2091

Link

https://rpbs.journals.ekb.eg/article_231964.html

Detail API

https://rpbs.journals.ekb.eg/service?article_code=231964

Order

4

Type

Mini-reviews

Type Code

534

Publication Type

Journal

Publication Title

Records of Pharmaceutical and Biomedical Sciences

Publication Link

https://rpbs.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023