Water is very essential for the human, animal and agriculture existence. Water supplies are exposed to contamination by different sources from industrial, pharmaceutical, agricultural and natural origins. Traditionally, analytical methods based on gas chromatography or liquid chromatography were used to
monitor water quality. The objective of this research was to monitor some OPPs and OCPs pesticides residues in Ismailia freshwater canal in the three governorates (Ismailia, Port Said and Suez) over a period started from May 2008 to January 2011 by GC using flame photometric detector (FPD) for OPPs and electron capture detector for OCPs pesticides. No OCPs pesticides residues were found in freshwater at quantification level of the GC method, however OPPs pesticides methamidophos (1.97 ngL-1) and ethoprophos (1.73 ngL-1) were detected in freshwater samples collected from Port Said governorate in February 2009.