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5916

Estrogen receptor alpha XbaI polymorphism is associated with higher relaxin-3 levels in women with metabolic syndrome

Article

Last updated: 22 Jan 2023

Subjects

-

Tags

Biochemistry and molecular biology

Abstract

Relaxin-3 is known to play a role in appetite regulation, increasing food intake and body weight. This study aimed to assess the relation of relaxin-3 with ERS1 XbaI and PvuII polymorphisms. One hundred female patients with metabolic syndrome were investigated. The genotypes of ESR1 XbaI and PvuII polymorphisms were assessed with PCR-RFLP. Serum relaxin-3 level was measured for all participants using ELISA. Higher relaxin-3 levels showed association with the minor GG genotype of ESR-1 XbaI polymorphism but not PvuII polymorphism.

DOI

10.21608/rpbs.2018.5916

Keywords

Plicosepalus acacia, Loranthaceae, antimicrobial activity

Authors

First Name

Eman

Last Name

Mehanna

MiddleName

T.

Affiliation

Department of Biochemistry, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt

Email

eman.taha@pharm.suez.edu.eg

City

-

Orcid

0000-0003-2759-2889

First Name

Noha

Last Name

Mesbah

MiddleName

M.

Affiliation

Department of Biochemistry, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt

Email

-

City

-

Orcid

-

First Name

Maivel

Last Name

Ghattas

MiddleName

H.

Affiliation

Department of Medical Biochemistry, Faculty of Medicine, Port Said University, Port Said, 42526, Egypt

Email

-

City

-

Orcid

-

First Name

Dina

Last Name

Abo-Elmatty

MiddleName

M.

Affiliation

Department of Biochemistry, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt

Email

-

City

-

Orcid

-

Volume

1

Article Issue

1

Related Issue

1063

Issue Date

2017-03-01

Receive Date

2016-11-28

Publish Date

2017-03-01

Page Start

17

Page End

21

Print ISSN

2536-9857

Online ISSN

2535-2091

Link

https://rpbs.journals.ekb.eg/article_5916.html

Detail API

https://rpbs.journals.ekb.eg/service?article_code=5916

Order

3

Type

Original Article

Type Code

532

Publication Type

Journal

Publication Title

Records of Pharmaceutical and Biomedical Sciences

Publication Link

https://rpbs.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023