This study investigates faculty members' practices of the 21^st Century skills in the institution of languages at the University of Tabuk from their point of view. The participants of the study were (151) faculty members. A self-completed questionnaire of five domains was developed then administered after verifying its validity and reliability. The findings revealed that faculty members' ratings of their practice for the 21^st Century skills were at a high degree. The practice of skills related to the Creativity and Innovation domain occupied the first rank, whereas they rated their practice of the skills related to ICT and digital domain at the last rank. Moreover, findings revealed that there are no statistically significant differences in faculty members' ratings about their practice of the 21^st Century skills attributed to the variables of gender, lingual status, or the interaction between them, whereas there were statistically significant differences related to the domain of ICT and digital skills, attributed to the variable of lingual status in favor of the non-native faculty members.