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196724

Role of vitamin D and insulin resistance in polycystic ovary syndrome

Article

Last updated: 23 Dec 2024

Subjects

-

Tags

Clinical Pharmacy

Abstract

Polycystic ovary syndrome (PCOS) is considered the commonest endocrinological disorder in childbearing age women with an incidence of 10%. Vitamin D has been shown in several studies to have a positive impact on female reproductive diseases, as well as PCOS. The diagnosis of PCOS, clinical symptoms, pathophysiology, hypovitaminosis D, insulin resistance, and the various methods for vitamin D and insulin assessment are all covered in this study. Androgen hypersecretion, oligo-ovulation, and/or ovarian morphologic features are used to diagnose this condition. Androgen excess, neuroendocrine causes, and insulin resistance are all part of the pathophysiology. Some female genital organs have been found to contain vitamin D receptors. Insulin regulates steroid biosynthesis in the ovaries and follicular maturation, so vitamin D is essential.

DOI

10.21608/jabps.2021.70702.1125

Keywords

25 (OH) D, polycystic ovary syndrome, Insulin Resistance, Vitamin D

Authors

First Name

Aya

Last Name

Abdallah

MiddleName

Mohammed

Affiliation

faculty of pharmacy minia university

Email

aya.mohammed1@mu.edu.eg

City

minia- egypt

Orcid

0000000313804932

First Name

Gamal

Last Name

Elazab

MiddleName

-

Affiliation

clinical pharmacy department, faculty of pharmacy, Tanta university

Email

gelazab@yahoo.com

City

-

Orcid

-

First Name

Mohammed

Last Name

Mosbeh

MiddleName

Hani

Affiliation

Obstetrics and Gynaecology department, Faculty of Medicine, Minia University

Email

dr.mohammedabdalla1954@gmail.com

City

-

Orcid

-

First Name

Hatem

Last Name

Sarhan

MiddleName

-

Affiliation

Pharmaceutics Department, Faculty of Pharmacy, Minia University, Minia, Egypt

Email

ha_sarhan@yahoo.com

City

Minia

Orcid

-

Volume

4

Article Issue

4

Related Issue

27944

Issue Date

2021-10-01

Receive Date

2021-04-03

Publish Date

2021-10-01

Page Start

186

Page End

194

Print ISSN

2535-1869

Online ISSN

2535-2040

Link

https://jabps.journals.ekb.eg/article_196724.html

Detail API

https://jabps.journals.ekb.eg/service?article_code=196724

Order

1

Type

Review Articles

Type Code

523

Publication Type

Journal

Publication Title

Journal of advanced Biomedical and Pharmaceutical Sciences

Publication Link

https://jabps.journals.ekb.eg/

MainTitle

Role of vitamin D and insulin resistance in polycystic ovary syndrome

Details

Type

Article

Created At

22 Jan 2023