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178715

Chemical and Biological Diversity in Nephthea Soft Corals in the Current Decade: A Review

Article

Last updated: 03 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Pharmacognosy

Abstract

Marine natural products play an important role within the innovation of lead compounds for drug development. The soft coral genus Nephthea has proven to be a treasurable source to discover new natural products with biological potentials. This review provides a survey of all metabolites isolated from the genus Nephthea in the current decade, along with their natural sources, chemical structures and biological potentials whenever possible. The current review aimed to compare chemical and biological diversity in the soft corals genus Nephthea. We listed 54 compounds including steroids and diterpenes. The steroids are the most abundant compounds of the genus Nephthea (74 %) followed by diterpenes (20%) and miscellaneous compounds (6%). The isolated compounds from genus Nephthea in the current decade have been shown different biological activities as cytotoxic against different cancer cell lines (29 compounds), as anti-inflammatory (13 compounds), antifouling (3 compounds) and antibacterial (2 compounds).

DOI

10.21608/jabps.2021.62966.1121

Keywords

Soft corals, Nephthea, Diterpenes, steroids, Cytotoxicity

Authors

First Name

Khaled

Last Name

Allam

MiddleName

M.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, South Valley University

Email

dr_khaled1986@yahoo.com

City

Qena

Orcid

0000-0002-3442-1124

First Name

Amgad

Last Name

Khedr

MiddleName

I.M.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Port Said University, Port Said P.O. Box 42526 Egypt. Faculty of Pharmacy, Horus University-Egypt, New Damietta, P.O. Box 34518 Egypt.

Email

a_mansour7799@yahoo.com

City

Port Said

Orcid

-

First Name

Ahmed

Last Name

Allam

MiddleName

E.

Affiliation

Pharmacognosy Dept., Faculty of Pharmacy, Al-Azhar University, Assiut Branch.

Email

aallam81@yahoo.co.uk

City

-

Orcid

-

First Name

Mohamed Salaheldin

Last Name

Abdelkader

MiddleName

A.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Sohag University, Nasr City, Eastern Avenue, P.O. Box 11432, Sohag, Egypt.

Email

m.salaheldin@pharm.sohag.edu.eg

City

-

Orcid

0000-0003-4793-7012

First Name

Ehab

Last Name

Elkhayat

MiddleName

S.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut P.O. Box 71524, Egypt.

Email

elkhayat@azhar.edu.eg

City

Assiut

Orcid

-

First Name

Mostafa

Last Name

Fouad

MiddleName

A.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Minia University, P.O. Box 61519 Minia, Egypt.

Email

m_fouad2000@yahoo.com

City

-

Orcid

0000-0002-3909-3537

Volume

4

Article Issue

3

Related Issue

26219

Issue Date

2021-07-01

Receive Date

2021-02-15

Publish Date

2021-07-01

Page Start

124

Page End

133

Print ISSN

2535-1869

Online ISSN

2535-2040

Article File

JABPS_Volume 4_Issue 3_Pages 124-133.pdf

PDF . 957.9kB

Link

https://jabps.journals.ekb.eg/article_178715.html

Detail API

https://jabps.journals.ekb.eg/service?article_code=178715

Order

2

Type

Review Articles

Type Code

523

Publication Type

Journal

Publication Title

Journal of advanced Biomedical and Pharmaceutical Sciences

Publication Link

https://jabps.journals.ekb.eg/

MainTitle

Chemical and Biological Diversity in Nephthea Soft Corals in the Current Decade: A Review

Details

Type

Article

Created At

22 Jan 2023