The main aim of this study was to differentiate among four Netherlands' genotypes of parsley (Moskurl 2 Petra, Moskurl 2 KRA USA, Gewone Dai 3 Rial 10 and Bravour) grown under Middle Egypt conditions in clay soil for the first time based on vegetative growth and oil composition. Gewone Dai 3 Rial 10 genotype is non-curly leafed, while the others are curly-leafed varieties. A field experiment was achieved during the two successive winter seasons of 2015/2016 and 2016/2017. This comparative study included horticultural characteristics (e.g. fresh plant weight (g), total yield of fresh leaves (ton/fed), shoot length (cm), total soluble solids (TSS) and leaves water content) in addition to the chemical profile of the essential oil. Myristicin and apiol were estimated because of their importance as cancer chemo-preventive agents. They improve the quality of parsley, which is produced in Egypt. The Gewone Dai 3 Rial 10 genotype showed the highest values of all growth characteristics in the two successive seasons. While, Moskrul 2 Petra gave the highest percentage of myristicin (33.91%) followed by Moskrul 2 KRA USA (33.22%), Bravour (29.30 %), Gewone Dai 3 Rial 10 (28.51%). While, Moskrul 2 KRA USA gave the highest apiol content (3.52%). This could also support the Egyptian income from their exportation as dried herb or essential oil or as food supplement or myristicin production.