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77451

Improving Skin Hardness and Thickness using a combination of Omega-3 Fatty Acid and Aloe Vera Oil: Pilot study

Article

Last updated: 03 Jan 2025

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Subjects

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Tags

Clinical Pharmacy

Abstract

Background/Aims: Maintaining skin elasticity and hardness is one way of keeping younger skin. This study investigates the topical effects of Aloe Vera (AV) alone and accompanied with Omega-3 (O-3) on skin hardness and thickness.
Method: Healthy females were randomly selected and divided into two groups (15 in each group) for a double-blind controlled study. All volunteers, between 18-25 years of age, were not pregnant or suffering from any medical illness. Both groups were asked to put formulations having similar appearance on the skin of forearm for 30 days. A prepared skin formulation containing AV oil only was considered baseline. The other group was treated with AV oil and O-3 mixture. Skin elasticity and hardness were measured using Digital Durometer and Diagnostic Ultrasound System.
Results: Compared to baseline, skin elasticity & hardness significantly improved at the end of the study in both AV and the combination groups. There was a slight synergistic effect of combining O-3 and AV on both elasticity and hardness.
Conclusion: The study is the first of its kind exploring the possible use of AV and O-3 topically to reverse the signs of aging on skin thickness. At the end of trial period improvements in skin thickness were noticed.

DOI

10.21608/jabps.2020.21568.1065

Keywords

skin, Omega3, Aloe vera, pilot study

Authors

First Name

Maha

Last Name

AlRasheed

MiddleName

M.

Affiliation

Department of Clinical Pharmacy, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11459, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Lina

Last Name

Hammad

MiddleName

F.

Affiliation

Department of Radiological Science, College of Applied Medical Sciences, King Saud University, P.O. Box 22452, Riyadh 11459, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Abeer

Last Name

Altaweel

MiddleName

F.

Affiliation

Department of Clinical Pharmacy, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11459, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Alaa

Last Name

Assiri

MiddleName

A.

Affiliation

Department of Clinical Pharmacy, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11459, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Albatool

Last Name

Bin Ajlan

MiddleName

A.

Affiliation

Department of Clinical Pharmacy, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11459, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Rawan

Last Name

Almugbel

MiddleName

A.

Affiliation

Department of Clinical Pharmacy, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11459, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Shaikha

Last Name

Aldukhail

MiddleName

Y.

Affiliation

Department of Clinical Pharmacy, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11459, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Norah

Last Name

Abanmy

MiddleName

O.

Affiliation

Department of Clinical Pharmacy, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11459, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Gamal

Last Name

Shazly

MiddleName

A.

Affiliation

Department of Pharmaceutics, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh 11459, Saudi Arabia, Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University 71526, Assiut, Egypt

Email

gaahmed@ksu.edu.sa

City

-

Orcid

-

Volume

3

Article Issue

2

Related Issue

11874

Issue Date

2020-04-01

Receive Date

2019-12-27

Publish Date

2020-04-01

Page Start

60

Page End

64

Print ISSN

2535-1869

Online ISSN

2535-2040

Article File

JABPS_Volume 3_Issue 2_Pages 60-64.pdf

PDF . 649.0kB

Link

https://jabps.journals.ekb.eg/article_77451.html

Detail API

https://jabps.journals.ekb.eg/service?article_code=77451

Order

3

Type

Original Article

Type Code

522

Publication Type

Journal

Publication Title

Journal of advanced Biomedical and Pharmaceutical Sciences

Publication Link

https://jabps.journals.ekb.eg/

MainTitle

Improving Skin Hardness and Thickness using a combination of Omega-3 Fatty Acid and Aloe Vera Oil: Pilot study

Details

Type

Article

Created At

22 Jan 2023