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Lipid profiling, phenolic content and antioxidant activity of the endophytic fungus Alternaria sp. isolated from Dracaena plant

Article

Last updated: 03 Jan 2025

Subjects

-

Tags

Pharmacognosy

Abstract

The aim of this study is to present the lipid profile along with the total phenolic contents and antioxidant activities of the ethyl acetate (EtOAc) and methanol (MeOH) extracts of the endophytic fungus Alternaria sp. isolated from Dracaena sp. leaves (Family: Asparagaceae). GC/MS analysis of the petroleum ether (pet. ether) fraction demonstrated high contents of oleic (23.15%), palmitic (23.33%), and linoleic (43.92%) acids. The EtOAc and MeOH extracts displayed a high total phenolic content, which was established by the Folin-Ciocaltue method. Moreover, the EtOAc extract showed considerable free radical scavenging activity (IC50= 0.52 mg/ml) using the DPPH assay and also exhibited substantial reducing power (13.322 mg Ascorbic equiv./g dried extract) by means of the phosphomolybdate complex assay.

Keywords

Endophytic fungi, Total phenolic content, Antioxidant activity, Lipid profile, Alternaria sp

Authors

First Name

Alyaa

Last Name

Ibrahim

MiddleName

H.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Sohag University, 82524 Sohag, Egypt

Email

dralyaahatem@gmail.com

City

-

Orcid

-

First Name

Eman

Last Name

Attia

MiddleName

Z.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt

Email

eshihata@yahoo.com

City

-

Orcid

-

First Name

Usama

Last Name

Abdelmohsen

MiddleName

R.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt

Email

usamaramadan80@gmail.com

City

-

Orcid

-

First Name

Samar

Last Name

Desoukey

MiddleName

Y.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt

Email

drsamaryehia@gmail.com

City

-

Orcid

0000-0002-4462-9674

First Name

Ehab

Last Name

Elkhayat

MiddleName

S.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut 71524, Egypt

Email

khayat71@yahoo.com

City

-

Orcid

-

First Name

Mostafa

Last Name

Fouad

MiddleName

A.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt

Email

m_fouad2000@yahoo.com

City

-

Orcid

0000-0002-3909-3537

First Name

Mohamed

Last Name

Kamel

MiddleName

S.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.

Email

mskamel@yahoo.com

City

-

Orcid

-

Volume

1

Article Issue

1

Related Issue

1479

Issue Date

2018-06-01

Receive Date

2018-04-04

Publish Date

2018-06-01

Page Start

13

Page End

16

Print ISSN

2535-1869

Online ISSN

2535-2040

Link

https://jabps.journals.ekb.eg/article_7669.html

Detail API

https://jabps.journals.ekb.eg/service?article_code=7669

Order

3

Type

Short Communication.

Type Code

525

Publication Type

Journal

Publication Title

Journal of advanced Biomedical and Pharmaceutical Sciences

Publication Link

https://jabps.journals.ekb.eg/

MainTitle

Lipid profiling, phenolic content and antioxidant activity of the endophytic fungus Alternaria sp. isolated from Dracaena plant

Details

Type

Article

Created At

22 Jan 2023