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86751

THE UTILITY OF MICHAEL CONDENSATION FOR THE SYNTHESIS OF MACROMOLECULE SURFACTANTS FROM AZO-NAPHTHOLS AS POSSIBLE ANTIMICROBIALS

Article

Last updated: 03 Jan 2025

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-

Tags

Chemistry

Abstract

 ((E)-4-(pyridin-3-yldiazenyl)naphthalen-1-ol) and (4-((E)–pyridin-3-yldiazenyl)– 8-((Z)-pyridin-3yldiazenyl)naphthalene-1,5-diol) (IIIa, b) were prepared. Condensation of (IIIa, b) with 2-(pyridin-4ylmethylene) malononitrile (V) under Michael reaction conditions gave the corresponding bezo[h]chromene and dihydrochromene[8,7-h] chromene derivatives (VIa, b). The cationic derivatives for (IIIa, b) and (VIa, b) were obtained by quaternization as (IVa,b) and (VIIa,b). The structures obtained were confirmed form IR, 1HNMR and mass spectra studies. The antimicrobial activities were also studied and have been found that; the cationic dyes (IVa,b) and (VIIa) exhibit promising results against Candida albicans. 

DOI

10.21608/absb.2019.86751

Keywords

Pyridinyldiazenylnaphthols, cationic azo dyes, antimicrobial activity

Authors

First Name

Ahmed

Last Name

Hammam

MiddleName

-

Affiliation

chemistry department, faculty of science, azhar university (boys), cairo

Email

hammam_ahm@yahoo.com

City

-

Orcid

-

First Name

A.

Last Name

El-Tabei

MiddleName

S.

Affiliation

Egyptian Petroleum Research Institute (EPRI), Nasr City, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

M.

Last Name

Hegazy

MiddleName

A.

Affiliation

Egyptian Petroleum Research Institute (EPRI), Nasr City, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

Mahmoud

Last Name

Mohamed

MiddleName

B.

Affiliation

Faculty of Science, Al-zhar University, Chemistry Dept., Nasr City, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

M.

Last Name

Sadeq

MiddleName

A.

Affiliation

Faculty of Science, Al-zhar University, Chemistry Dept., Nasr City, Cairo, Egypt

Email

-

City

-

Orcid

-

Volume

30

Article Issue

2-A

Related Issue

13037

Issue Date

2019-12-01

Receive Date

2019-08-18

Publish Date

2019-12-01

Page Start

17

Page End

26

Print ISSN

1110-2535

Online ISSN

2636-3305

Article File

ABSB_Volume 30_Issue 2-A_Pages 17-26.pdf

PDF . 851.5kB

Link

https://absb.journals.ekb.eg/article_86751.html

Detail API

https://absb.journals.ekb.eg/service?article_code=86751

Order

3

Type

Original Article

Type Code

520

Publication Type

Journal

Publication Title

Al-Azhar Bulletin of Science

Publication Link

https://absb.journals.ekb.eg/

MainTitle

THE UTILITY OF MICHAEL CONDENSATION FOR THE SYNTHESIS OF MACROMOLECULE SURFACTANTS FROM AZO-NAPHTHOLS AS POSSIBLE ANTIMICROBIALS

Details

Type

Article

Created At

22 Jan 2023