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33806

EXTERACELLULAR L-ASPARAGINASE FROM LOCAL SOIL BACTERIA: PRODUCTION AND OPTIMIZATION OF PHYSIOLOGICAL CONDITION

Article

Last updated: 03 Jan 2025

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Subjects

-

Tags

Botany
Microbiology
Zoology

Abstract

L-asparaginase produced by Bacillushalotolerans OHEM18 finds broad applications due to its hydrolysis activity so used as therapeutic agents in combination with additional medications in the cure of acute lymphoblastic leukemia and also in food processing. In the present study, L-asparaginase production was optimizedand the optimum factors for production under submerged fermentation (SMF) of the asparaginase were pH 7.0 after 28h using glucose and asparagine as carbon and nitrogen sources, respectively while bagasse was the best inducer for L-asparaginase production under SSF.

DOI

10.21608/absb.2018.33806

Keywords

L-asparaginase, enzyme production, submerged fermentation and solid state fermentation

Authors

First Name

Hanaa

Last Name

Orabi

MiddleName

M.

Affiliation

Botany & Microbiology Department, Faculty of Science, Al-Azhar University (Girls Branch)

Email

-

City

-

Orcid

-

First Name

Esmail

Last Name

El-Fakrany

MiddleName

M.

Affiliation

Protein Research Department, Genetic Engineering and Biotechnology Research Institute, City for Scientific Research and Technology Applications, Alexandria, Egypt.

Email

-

City

-

Orcid

-

First Name

Eman

Last Name

Abdel Khalek

MiddleName

S.

Affiliation

Botany & Microbiology Department, Faculty of Science, Al-Azhar University (Girls Branch)

Email

-

City

-

Orcid

-

First Name

Aziza

Last Name

El-Kasaby

MiddleName

M.

Affiliation

Botany & Microbiology Department, Faculty of Science, Al-Azhar University (Girls Branch)

Email

-

City

-

Orcid

-

First Name

Nagwa

Last Name

Sidkey

MiddleName

M.

Affiliation

Botany & Microbiology Department, Faculty of Science, Al-Azhar University (Girls Branch)

Email

-

City

-

Orcid

-

Volume

29

Article Issue

Issue 2-C

Related Issue

5649

Issue Date

2018-12-01

Receive Date

2018-08-21

Publish Date

2018-12-24

Page Start

1

Page End

7

Print ISSN

1110-2535

Online ISSN

2636-3305

Article File

ABSB_Volume 29_Issue Issue 2-C_Pages 1-7.pdf

PDF . 330.9kB

Link

https://absb.journals.ekb.eg/article_33806.html

Detail API

https://absb.journals.ekb.eg/service?article_code=33806

Order

1

Type

Original Article

Type Code

520

Publication Type

Journal

Publication Title

Al-Azhar Bulletin of Science

Publication Link

https://absb.journals.ekb.eg/

MainTitle

EXTERACELLULAR L-ASPARAGINASE FROM LOCAL SOIL BACTERIA: PRODUCTION AND OPTIMIZATION OF PHYSIOLOGICAL CONDITION

Details

Type

Article

Created At

22 Jan 2023