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11640

SYNTHESIS OF SOME NOVEL PYRIDINE, THIOPHENE, THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES CONTAINING BENZOFURANYL MOIETY

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Last updated: 03 Jan 2025

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Abstract

Interaction of 2-[1-(4,6-dimethoxybenzofuran-5-yl)ethylidine]malononitrile (1) with phenylisocyanate, phenylhydrazine, carbon disulphide and arylidenemalono-nitrile afforded the corresponding pyridine 2, pyrido[2,3-d] pyrimidine 3, phenylhydrazone 4,pyridine 2,6-dithione 8 and benzene dicarbonitrile 9 derivatives . Treatment of 1 with elemental sulfur under Gewald reaction conditions furnished 2-amino-4-(4,6-dimethoxybenzofuran-5-yl)thiophen-3-carbonitrile 11 which used as starting material in the synthesis of thienopyrimidine 14 and thienopyridine 15 derivatives.

DOI

10.21608/absb.2006.11640

Keywords

Pyridine, THIOPHENE, THIENOPYRIMIDINE, THIENOPYRIDINE, BENZOFURANYL

Authors

First Name

J.

Last Name

MICKY

MiddleName

A.

Affiliation

Chemistry Department, Faculty of Science (Girl's), Al-Azhar University–Nasr City, Cairo, Egypt.

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City

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Orcid

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First Name

N.

Last Name

SALEH

MiddleName

M.

Affiliation

Chemistry Department, Faculty of Science (Girl's), Al-Azhar University–Nasr City, Cairo, Egypt.

Email

-

City

-

Orcid

-

First Name

N.

Last Name

SHEMISS

MiddleName

M.

Affiliation

Chemistry Department, Faculty of Science (Girl's), Al-Azhar University–Nasr City, Cairo, Egypt.

Email

-

City

-

Orcid

-

First Name

S.

Last Name

MOHAMED

MiddleName

A.

Affiliation

Chemistry Department, Faculty of Science (Girl's), Al-Azhar University–Nasr City, Cairo, Egypt.

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-

City

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Volume

17

Article Issue

Issue 1-A

Related Issue

2157

Issue Date

2006-06-01

Receive Date

2006-01-10

Publish Date

2006-06-01

Page Start

65

Page End

75

Print ISSN

1110-2535

Online ISSN

2636-3305

Article File

ABSB_Volume 17_Issue Issue 1-A_Pages 65-75.pdf

PDF . 379.2kB

Link

https://absb.journals.ekb.eg/article_11640.html

Detail API

https://absb.journals.ekb.eg/service?article_code=11640

Order

5

Type

Original Article

Type Code

520

Publication Type

Journal

Publication Title

Al-Azhar Bulletin of Science

Publication Link

https://absb.journals.ekb.eg/

MainTitle

SYNTHESIS OF SOME NOVEL PYRIDINE, THIOPHENE, THIENOPYRIMIDINE AND THIENOPYRIDINE DERIVATIVES CONTAINING BENZOFURANYL MOIETY

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Type

Article

Created At

22 Jan 2023