Some dihydrazones and their copper complexes were synthesized in order to study their molecular structures and antimicrobial activities. The dihydrazones were prepared by refluxing malonyldihydrazide with some aldehydes in absolute ethyl alcohol. The complexes were prepared by indirect method where copper acetate was refluex with the aldehydes and the solution was treated with malonyldihydrazides. All the complexes are characterized by elemental analysis, magnetic, electronic and IR data. Biological activities and their statistical analysis were also determined.