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10797

COBALT(II) COMPLEX BINDING WITH COPOLYMER AS A PROFICIENT CATALYST FOR OXIDATION OF CATECHOL

Article

Last updated: 22 Jan 2023

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Tags

Chemistry

Abstract

The metallopolymer cobalt(II) complex of a simple pyridine- and amide-containing copolymer (CoII-P9) was prepared and characterized with IR and 1H NMR.  The 1H NMR spectrum of the copolymer indicates that the average repeating unit of the copolymer P9 is vinyl pyridine:acrylamide = 5:1.  The IR spectra suggest that cobalt is bound to the polymer through the pyridine nitrogen atom and the acrylamide does not participate in the binding.  The oxidation of catechol by CoII-P9 in the presence of 7.5 mM H2O2 exhibits enzyme-like pre-equilibrium kinetics, yielding kcat = 0.026 ± 0.3 s–1, dissociation constant K′ = 1.9 ± 0.6 mM, and kcat /K′ = 13.7 M–1s–1.  The inert 4,5-dichlorocatechol is also oxidized by CoII-P9 in absence of H2O2 to afford rate constants of kcat = (3.1 ± 0.2) × 10–4 s–1 and K′  = 0.7 ± 0.1 mM. This study has introduced a simple catalase-like system to explore the mechanism of Co(II)-centered redox chemistry and its application.

DOI

10.21608/absb.2008.10797

Keywords

Catechol, oxidase, copolymer, vinyl pyridine, inhibition

Authors

First Name

AHMED

Last Name

HANAFY

MiddleName

I.

Affiliation

Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt

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Orcid

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Volume

19

Article Issue

Issue A-2

Related Issue

2052

Issue Date

2008-12-01

Receive Date

2008-08-01

Publish Date

2008-12-01

Page Start

83

Page End

94

Print ISSN

1110-2535

Online ISSN

2636-3305

Link

https://absb.journals.ekb.eg/article_10797.html

Detail API

https://absb.journals.ekb.eg/service?article_code=10797

Order

7

Type

Original Article

Type Code

520

Publication Type

Journal

Publication Title

Al-Azhar Bulletin of Science

Publication Link

https://absb.journals.ekb.eg/

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Article

Created At

22 Jan 2023