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SYNTHESIS, SURFACE AND ANTIMICROBIAL PROPERTIES OF FATTY MORPHOLIDE AND PIPERIDIDE DERIVATIVES

Article

Last updated: 03 Jan 2025

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-

Tags

Chemistry

Abstract

Unsaturated fatty N-acyl morpholide and piperidide derivatives were prepared by the reaction of the acid chloride of oleic and linoleic acids as well as the mixed fatty acid chlorides of olive, linseed and castor oils with morpholine and piperidine. The sodium bisulfite and mercapto acetic acid were added to the prepared unsaturated fatty amides to give sulfonated and methylthiocarboxylate morpholide and piperidide derivatives. These derivatives were characterized using infrared (IR), 1H nuclear magnetic resonance (NMR) and mass spectroscopy (MS), they showed excellent lowering power of surface tension, foaming stability and emulsifying property. On the other hand, these derivatives showed a broad antimicrobial spectra as high as chloramphenicol against all the tested microorganisms. It was found that compounds containing a carboxylate hydrophilic group were less efficient than those with a suflonate group with respect to foaming power, foam stability, emulsification and antimicrobial effect.

DOI

10.21608/absb.2008.9915

Keywords

FATTY MORPHOLIDE, PIPERIDIDE DERIVATIVES

Authors

First Name

B.

Last Name

EL-SADEK

MiddleName

M.

Affiliation

Chemistry Department, Faculty of Science (Girls), Al-Azhar University, Nasr City, Egypt

Email

-

City

-

Orcid

-

First Name

F.

Last Name

ABDEL SALAM

MiddleName

H.

Affiliation

Chemistry Department, Faculty of Science (Girls), Al-Azhar University, Nasr City, Egypt

Email

-

City

-

Orcid

-

First Name

E.

Last Name

KANDEEL

MiddleName

M.

Affiliation

Chemistry Department, Faculty of Science (Girls), Al-Azhar University, Nasr City, Egypt

Email

-

City

-

Orcid

-

First Name

S.

Last Name

BAKR

MiddleName

A.

Affiliation

Chemistry Department, Faculty of Science (Girls), Al-Azhar University, Nasr City, Egypt

Email

-

City

-

Orcid

-

Volume

19

Article Issue

Issue 1-A

Related Issue

1639

Issue Date

2008-06-01

Receive Date

2008-01-26

Publish Date

2008-06-01

Page Start

223

Page End

232

Print ISSN

1110-2535

Online ISSN

2636-3305

Article File

ABSB_Volume 19_Issue Issue 1-A_Pages 223-232.pdf

PDF . 140.5kB

Link

https://absb.journals.ekb.eg/article_9915.html

Detail API

https://absb.journals.ekb.eg/service?article_code=9915

Order

15

Type

Original Article

Type Code

520

Publication Type

Journal

Publication Title

Al-Azhar Bulletin of Science

Publication Link

https://absb.journals.ekb.eg/

MainTitle

SYNTHESIS, SURFACE AND ANTIMICROBIAL PROPERTIES OF FATTY MORPHOLIDE AND PIPERIDIDE DERIVATIVES

Details

Type

Article

Created At

22 Jan 2023