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EFFECT OF LIPOPOLYSACCHARIDE AND THE AMELIORATIVE EFFECT OF THE ANTIOXIDANT MELATONIN ON SOME PHYSIOLOGICAL PARAMETERS OF SHEEP EMBRYOS

Article

Last updated: 03 Jan 2025

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Subjects

-

Tags

Botany
Microbiology
Zoology

Abstract

As known, lipopolysaccharide (LPS) is a toxin that is secreted from gram negative bacteria as E. coli which is present in the gut of animals like sheep and it may be transported to the embryo through the blood affect the brain and other organs. Little is known about the effect of LPS on liver and kidney function or hematological parameters. In the present study we found that melatonin treatment improved most of the liver functions that affected by LPS injection and also improve kidney function, although LPS injection was found to lead to a decrease of createnine, urea and uric acid for unknown reason. concurrently injection of melatonin plus LPS led to decreasing most of blood indices while increasing of RBCs count and WBCs count. So, we concluded that usage of melatonin as general antioxidant is useful against LPS toxicity.

DOI

10.21608/absb.2012.7210

Keywords

LPS, Ameliorative, Melatonin, kidney, Liver, Blood

Authors

First Name

DIAA

Last Name

AHMED

MiddleName

F.

Affiliation

Zoology Department, Faculty of Science, Al -Azhar University, Cairo, Egypt.

Email

-

City

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Orcid

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First Name

SAMIR

Last Name

ZAAHKOUK

MiddleName

A.

Affiliation

Zoology Department, Faculty of Science, Al -Azhar University, Cairo, Egypt.

Email

-

City

-

Orcid

-

First Name

EL-YAMANI

Last Name

EL-ZWAHRY

MiddleName

I.

Affiliation

Zoology Department, Faculty of Science, Al -Azhar University, Cairo, Egypt.

Email

-

City

-

Orcid

-

Volume

23

Article Issue

Issue 2-C

Related Issue

1368

Issue Date

2012-12-01

Receive Date

2012-01-01

Publish Date

2012-12-01

Page Start

1

Page End

12

Print ISSN

1110-2535

Online ISSN

2636-3305

Article File

ABSB_Volume 23_Issue Issue 2-C_Pages 1-12.pdf

PDF . 170.7kB

Link

https://absb.journals.ekb.eg/article_7210.html

Detail API

https://absb.journals.ekb.eg/service?article_code=7210

Order

1

Type

Original Article

Type Code

520

Publication Type

Journal

Publication Title

Al-Azhar Bulletin of Science

Publication Link

https://absb.journals.ekb.eg/

MainTitle

EFFECT OF LIPOPOLYSACCHARIDE AND THE AMELIORATIVE EFFECT OF THE ANTIOXIDANT MELATONIN ON SOME PHYSIOLOGICAL PARAMETERS OF SHEEP EMBRYOS

Details

Type

Article

Created At

22 Jan 2023