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7025

SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW COUMARIN, PYRIDINE, 1,2,3-TRIAZOLE, THIAZOLIDINONE, PYRAZOLOTRIAZINE, THIOPHENE AND THIAZOLE DERIVATIVES BEARING CARBONYLHYDRAZONOETHYLPHENYLTOSYLATE MOIETY

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Last updated: 22 Jan 2023

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Chemistry

Abstract

A number of novel coumarin (4), pyridinone (5a,b), thiophenopyridinone (6), 1,2,3-triazole (7), pyrazolotriazine (10), thiazole (11,14a,b,15), thiophene (12), thiazolidinone (20,21,23) derivatives were synthesized via interaction of 4-(1-(2-(2-cyanoacetyl)hydrazono)ethyl)phenyltosylate (3) with different nucleophilic reagents. The structures of the newly synthesized compounds were confirmed by elemental analyses IR, 1H-NMR and mass spectral data. All compounds were evaluated for their antimicrobial activities.

DOI

10.21608/absb.2011.7025

Keywords

yanoacetylhydrazonoethylphenyltosylate, Pyridine, thiazole, Coumarin, THIOPHENE, pyrazolotriazine, thiazolidinone

Authors

First Name

MAHMOUD

Last Name

ABDELALL

MiddleName

M.

Affiliation

Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt.

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First Name

SHABAN

Last Name

MOHAMED

MiddleName

I.

Affiliation

Technology Engineering Institute, Tamoh, Giza, Egypt.

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City

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Orcid

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First Name

AHMED

Last Name

HALAWA

MiddleName

H.

Affiliation

Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt.

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Orcid

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First Name

AHMED

Last Name

HASSAN

MiddleName

A.

Affiliation

Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt.

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-

City

-

Orcid

-

First Name

MOHAMED

Last Name

ELNASSAG

MiddleName

A.

Affiliation

Chemistry Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, Egypt.

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Volume

22

Article Issue

Issue 2-A

Related Issue

1329

Issue Date

2011-12-01

Receive Date

2011-08-03

Publish Date

2011-12-01

Page Start

165

Page End

180

Print ISSN

1110-2535

Online ISSN

2636-3305

Article File

ABSB_Volume 22_Issue Issue 2-A_Pages 165-180.pdf

PDF . 263.1kB

Link

https://absb.journals.ekb.eg/article_7025.html

Detail API

https://absb.journals.ekb.eg/service?article_code=7025

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Original Article

Type Code

520

Publication Type

Journal

Publication Title

Al-Azhar Bulletin of Science

Publication Link

https://absb.journals.ekb.eg/

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Article

Created At

22 Jan 2023