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6423

THE PRODUCTION OF ANTIMICROBIAL AGENTS BY WILD & RADIO ACTIVATED ACTINOBACTER SP.

Article

Last updated: 22 Jan 2023

Subjects

-

Tags

Botany
Microbiology
Zoology

Abstract

The production of several volatile substances like Geosmin responsible of the characteristic wet earth odor  distributed in terrestrial and aquatic ecosystems, especially in soil. Members of this group are produce clinically useful antitumor drugs such as Anthracyclines, Antimetabolites, Arzinophilin, Mitomycins and Vancomycins .
DNA cleavage by topoisomerase I or II inhibition , Mitochondria permeabilization inhibition and inhibiting tumor-induced angiogenesis .
Isolation , Purification of Actinobacter from different sources and Determination of biological activities ( Antimicrobial / Anti-tumor ) .
Optimization of production media ( natural and synthetic) of the promising bioactive compounds ( Antimicrobial / Anti-tumor ).
Finally, Determination of the anti-tumor activity of the bioactive compound (s) of Actinobacter against different tumors.

DOI

10.21608/absb.2013.6423

Keywords

Antimicrobial agents, ACTINOBACTER SP

Authors

First Name

MAGED

Last Name

AHMED

MiddleName

S.

Affiliation

Botany Deptartment, Faculty of Sciences, Ben Sewef University, Ben Sewef, Egypt.

Email

-

City

-

Orcid

-

First Name

MEDHAT

Last Name

ABD EL-MOHSEIN

MiddleName

ABD EL- FATTAH

Affiliation

Botany Deptartment, Faculty of Sciences, Ben Sewef University, Ben Sewef, Egypt.

Email

-

City

-

Orcid

-

First Name

MOSTAFA

Last Name

SALAMA

MiddleName

M.

Affiliation

Botany Deptartment, Faculty of Sciences, Ben Sewef University, Ben Sewef, Egypt.

Email

-

City

-

Orcid

-

First Name

HUSSEIN

Last Name

EL-KABBANY

MiddleName

M.

Affiliation

Health Radiation Research Department, National Center for Radiation Research and Technology. Atomic Energy Authority, Cairo, Egypt.

Email

-

City

-

Orcid

-

Volume

24

Article Issue

Issue 2-C

Related Issue

1322

Issue Date

2013-12-01

Receive Date

2013-08-11

Publish Date

2013-12-01

Page Start

109

Page End

120

Print ISSN

1110-2535

Online ISSN

2636-3305

Link

https://absb.journals.ekb.eg/article_6423.html

Detail API

https://absb.journals.ekb.eg/service?article_code=6423

Order

19

Type

Original Article

Type Code

520

Publication Type

Journal

Publication Title

Al-Azhar Bulletin of Science

Publication Link

https://absb.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023