A series of complexes of Co(II), Ni(II), Cu(II), Zn(II), Cd(II) have been synthesized with two hydrazones derived from Isatin with salicylaldehyde (HL_a) and 2,4-dinitro phenyl hydrazine (L_b). The complexes have been characterized by the elemental analysis, spectral (FTIR, Mass, Electronic, ¹HNMR, ESR), Thermal analysis (TGA&DTA), Magnetic moments and conductance measurements. The proposed structures of the prepared complexes were octahedral (Co(II)-HL_a), tetrahedral for Ni(II), Zn(II), Cd(II)-HL_a complexes and square planar for (Cu(II)-HL_a, L_b Zn(II)-L_b complexes. The synthesized ligands (HL_a and L_b) were tested for their antibacterial activities. Only HL_a ligand displayed activity against staphylococcus aureas (g +ve)