Medicinal and aromatic plants are important sources for the production of many pharmaceutical compounds such as antibiotic drugs. The presented study aims to survey and record the various medicinal plant species in Al-Mandaq Governorate - Al-Baha region - Kingdom of Saudi Arabia with a number of targeted locations such as Mashnaih, Darake and Khleb valleys, Medhas and Darake Dams in 2018 and 2019. 160 species of vascular plants belonging to 52 plant families were surveyed and recorded. The study proved that the Poaceae family is the most contain of the plant species (22 species, 13.7%), followed by the Asteraceae family (19 species, 11.8%), then the Fabaceae family (11 species, 6.8%). According to the life forms, the annual plants represent the highest percentage among the recorded plants (56 species, 35%), followed by the perennial herbs (48 species, 30%), then shrubs (26 species, 16.25%) and the least recorded species are bi-perennials (5 species, 3.12 %), Palms and cactus (one species, 0.6%). The recorded results and statistics represent a database of the floral content in the study area and also provide important information for the recorded plants and their uses in the fields of food, ornamental and biological applications.