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12509

EVALUATION OF SAFETY AND EFFICACY OF CAUDAL ADMINISTRATION OF BUPIVACAINE/ DEXMEDETOMIDINE VERSUS BUPIVACAINE/FENTANYL IN PEDIATRIC UNILATERAL HERNIA REPAIR

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Last updated: 22 Jan 2023

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Abstract

Background& Aim: Effective postoperative analgesia is important from the patient's perspective and can also improve clinical outcomes. This study aimed to compare the effect of caudal bupivacaine plus fentanyl versus caudal bupivacaine plus dexmedetomidine on the recovery of anesthesia, postoperative analgesia required, hemodynamic stability& neurological complications in pediatric unilateral hernia repair patients. Patients & Methods: 50 (ASA) grade I patients, aged 2-4 years with uncomplicated unilateral inguinal hernias treated as day cases were randomly allocated into either; Group I (BF), received Bupivacaine 0.25 % 1 ml\ kg, and fentanyl 1 μg\ kg, or Group 2 (BD), received Bupivacaine 0.25 % 1 ml\ kg, and dexmedetomidine 1 μg\ kg. Patients were evaluated in terms of pain and sedation using FLACC scale and Ramsay Sedation Scale, respectively. Haemodynamic stability and Neurological complications were assessed during the postoperative period and one day postoperatively.

DOI

10.21608/ajps.2015.12509

Keywords

Dexmeditomedine, Fentanyl, Pediatric, Inguinal hernia, Caudal anaesthesia

Authors

First Name

Reem

Last Name

Sleem,

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Affiliation

Department of Clinical Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt

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Volume

51

Article Issue

1

Related Issue

2386

Issue Date

2015-03-01

Receive Date

2018-09-04

Publish Date

2015-03-01

Page Start

185

Page End

197

Print ISSN

1110-1644

Online ISSN

2535-1958

Link

https://ajps.journals.ekb.eg/article_12509.html

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https://ajps.journals.ekb.eg/service?article_code=12509

Order

14

Type

Original Article

Type Code

518

Publication Type

Journal

Publication Title

Al-Azhar Journal of Pharmaceutical Sciences

Publication Link

https://ajps.journals.ekb.eg/

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Article

Created At

22 Jan 2023