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SYNTHESIS OF NEW [1,5]-BENZODIAZEPINE DERIVATIVES CATALYZED BY VARIOUS ALIPHATIC ACIDS

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Last updated: 03 Jan 2025

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Abstract

A series of some new[1,5]benzodiazepines has been synthesized using condensation reaction of o-phenelendiamine  with different newly synthesized quinolinyl ketones and effect of different aliphatic acids used as a catalyst was studied. Among the catalytic screened aliphatic acid, chloroacetic acid are a versatile catalyst that modify the yield (60-95%) in short reaction time. 

DOI

10.21608/ajps.2013.7099

Keywords

1, 5 – benzodiazepine, o-phenelendiamine, quinolinyl ketones, aliphatic acids

Authors

First Name

Kamal

Last Name

El-Gaml

MiddleName

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Affiliation

Organic chemistry department, Al-Azher University, Naser city, Cairo, 11884, Egypt

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Volume

48

Article Issue

2

Related Issue

1338

Issue Date

2013-09-01

Receive Date

2018-05-14

Publish Date

2013-09-01

Page Start

114

Page End

119

Print ISSN

1110-1644

Online ISSN

2535-1958

Article File

AJPS_Volume 48_Issue 2_Pages 114-119.pdf

PDF . 357.3kB

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https://ajps.journals.ekb.eg/article_7099.html

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https://ajps.journals.ekb.eg/service?article_code=7099

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Original Article

Type Code

518

Publication Type

Journal

Publication Title

Al-Azhar Journal of Pharmaceutical Sciences

Publication Link

https://ajps.journals.ekb.eg/

MainTitle

SYNTHESIS OF NEW [1,5]-BENZODIAZEPINE DERIVATIVES CATALYZED BY VARIOUS ALIPHATIC ACIDS

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Article

Created At

22 Jan 2023