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6969

SEMICARBAZONES AS ANTICONVULSANTS

Article

Last updated: 03 Jan 2025

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Abstract

Approximately 25% of epileptics' convulsions are inefficiently controlled by currently available remedies; therefore the preparation of new antiepileptic drugs is of great interest. Aryl semicarbazones can be considered a new class of compounds presenting anticonvulsant activity. In addition, they can be orally administered. Semicarbazones derived from aromatic and unsaturated carbonyl compounds as well as from other precursors are reviewed together with their anticonvulsant profile.

DOI

10.21608/ajps.2014.6969

Keywords

Semicarbazone, Anticonvulsant, pentylenetetrazole (PTZ), maximal electroshock (MES)

Authors

First Name

Mohamed

Last Name

Aboul-Enein

MiddleName

-

Affiliation

Medicinal and Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Dokki, Giza,12622, Egypt

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Orcid

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Volume

49

Article Issue

1

Related Issue

1336

Issue Date

2014-03-01

Receive Date

2018-05-13

Publish Date

2014-03-01

Page Start

220

Page End

241

Print ISSN

1110-1644

Online ISSN

2535-1958

Article File

AJPS_Volume 49_Issue 1_Pages 220-241.pdf

PDF . 472.4kB

Link

https://ajps.journals.ekb.eg/article_6969.html

Detail API

https://ajps.journals.ekb.eg/service?article_code=6969

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16

Type

Original Article

Type Code

518

Publication Type

Journal

Publication Title

Al-Azhar Journal of Pharmaceutical Sciences

Publication Link

https://ajps.journals.ekb.eg/

MainTitle

SEMICARBAZONES AS ANTICONVULSANTS

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Article

Created At

22 Jan 2023