Understanding the genetics mechanisms of flower and fruit development is very crucial for efficient breeding of many agronomical important crops. MADS-box group of transcription factors has been known for its significant contribution of controlling fruit development.  FRUITFULL (FUL) is one of the genes that plays important roles in this regard. For more understanding of FUL gene function in capsule dry-fruit development, this study used virus Induced Gene Silencing method to knockdown FUL gene expression in the newly developed model plant, Nicotiana obtusifolia. Treated plants exhibited delayed flowering, shorter inflorescence stems and longer fused sepal when compared to wild type and control group. However, no altered fruit phenotypes were observed among the treated N. obtusifolia plants. Downregulation of FUL gene in Nicotiana obtusifolia, allows us to assess a better understanding of its function in dry fruit species of the family Solanaceae.  It also suggests that FUL protein plays different roles in the development of dry versus fleshy fruits in Solanaceae.