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189731

Risk Factors of Post-Asphyxial Hypoxic-Ischemic Encephalopathy [PAHIE] Abha City – Southwestern Saudi Arabia: A Case-Control Study

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Last updated: 03 Jan 2025

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Abstract

A case-control study of neonatal encephalopathy was conducted in Abha General Hospital to determine some possible risk factors of encephalopathy. A total of 57 full term infants with evidence of neonatal encephalopathy at 6-24 hours after birth were recruited over a period of 3 years, and compared with the same number of a control group of normal newborns. The cumulative incidence of neonatal encephalopathy was 4.9 per 1000 live births [95% CI: 3.1 to 6.3]. Moderate or severe encephalopathy occurred in about 63% of all infants, with seizures in 67%. All of the 57 [100%] infants with encephalopathy required one or more of the resuscitation measures compared with 8 [14%] of the control. Significant antepartum risk factors of encephalopathy include: primiparity [OR=3.13], no accessibility to antenatal care [OR=1.89], and pregnancy-induced hypertension [OR=2.13]. Significant possible labor and delivery risk factors include: no cephalic presentation [OR=2.76], meconium stained amniotic fluid [OR=4.18], fetal bradycardia [OR=5.23], abnormal fetal heart rate [OR=2.34], antepartum haemorrhage [OR=4.32], instrumental delivery [OR=2.1], and prolonged 2nd stage of labor [OR=6.67]. In conclusion, both antepartum and intrapartum factors are important in the causation of neonatal encephalopathy in Abha City. Improvement of both antenatal care and care during delivery is a necessity.  

DOI

10.21608/jhiph.2004.189731

Keywords

risk factors, Post-Asphyxial Hypoxic-Ischemic Encephalopathy [PAHIE], Abha City, Saudi Arabia, case-control study

Authors

First Name

Mohammed

Last Name

Al-Shehri

MiddleName

A.

Affiliation

College of Medicine and Health Sciences, King Khalid University, Abha, Saudi Arabia

Email

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City

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Orcid

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First Name

Walid

Last Name

Eid

MiddleName

A.

Affiliation

Neonatology Unit, Abha General Hospital, MOH, Abha, Saudi Arabia

Email

-

City

-

Orcid

-

Volume

34

Article Issue

2

Related Issue

26024

Issue Date

2004-04-01

Receive Date

2021-08-17

Publish Date

2004-04-01

Page Start

413

Page End

424

Print ISSN

2357-0601

Online ISSN

2357-061X

Link

https://jhiphalexu.journals.ekb.eg/article_189731.html

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https://jhiphalexu.journals.ekb.eg/service?article_code=189731

Order

10

Type

Original Article

Type Code

511

Publication Type

Journal

Publication Title

Journal of High Institute of Public Health

Publication Link

https://jhiphalexu.journals.ekb.eg/

MainTitle

Risk Factors of Post-Asphyxial Hypoxic-Ischemic Encephalopathy [PAHIE] Abha City – Southwestern Saudi Arabia: A Case-Control Study

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Article

Created At

22 Jan 2023