Objectives: To assess impact of leukaemia on children and their families and to describe utilization and satisfaction with health services among acute leukaemic children. Methods: A descriptive study started Nov. 2004 for one year duration, included 163 cases (all acute leukaemic cases below the age of 15 attended in-and out-patient of University of Alexandria Paediatrics Hsospital, either newly diagnosed or for follow up). Questionnaire sheet administered by interview with the patient's mother included questions about disease impact on the child and his parents. Answers to questions on utilization of health services were blotted to a total score for mother satisfaction. Results: Overall health services were free of charge, (83.4%) of mothers received financial aid, but (93.3%) of families were affected financially, as (65.6%) were of low socioeconomic level. Psychological upset was almost the rule in relation to the patient and his family members. The learning process deteriorated in (63.8%) of cases. Most mothers (83.4%) complained that only some drugs are available, but only (22.7%) said that investigations were incomplete. The child club in the hospital was the only recreational mean and utilized by (41.1%) of cases. Highest satisfaction score was with services offered by physicians (art of medical care); lowest score was for the amount of food presented to patients. Conclusion: The leukaemic health problem influences the patient and his family's quality of life in a serious way, the child educational progress is affected as well. Patient's mother satisfaction is crucial and her recommendations to improve the quality of service are to be considered.