Background/Objective: Objective Structured Clinical Examinations (OSCEs) are an effective assessment strategy for assessing clinical skills and for highlighting curriculum problem areas Since its inception, the OSCE has been increasingly used to provide formative and summative assessment in various medical disciplines. Methods: The study was conducted at Critical Care Nursing and emergency Department, the Faculty of Nursing, Alexandria University, Specifically in emergency nursing course. Data were collected using questionnaire comprised 26 items to determine students' feedback in relation to OSCE as an assessment method in acute care. Results: The majority of students agreed that the OSCE was comprehensive and covered a wide range of knowledge and clinical skills taught and in addition the exam was less stressful than other exams and the students felt the OSCE exam highlighting their strengths and weaknesses. Moreover, the exam increased their self confidence to face real situations. Conclusion and Recommendations: OSCE as an assessment method is an effective method to test students' competencies and teachers can diagnose the teaching defects and OSCE provides opportunities for students to learn from mistakes and increase their self confidence. OSCE can be implemented in different nursing specialties.