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Maternal and Fetal Leptin Level Correlation with Fetal Macrosomia

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Last updated: 03 Jan 2025

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Abstract

Background: Leptin seems to be a critical factor for overall fetal development. Macrosomia may place the mother and fetus or neonate at risk for adverse outcomes. Objective: to test if leptin level is implicated in macrosomia. Methods: The sample comprised25 cases delivered full term normal weight infants, and 25 cases delivered full term macrosomicinfants. Maternal serum samples and fetal cord samples were withdrawn immediately after birth of the full term infants. Results: Fetal leptin level was higher in macrosomic infants than normal weight infants. No difference in maternal leptin level between both groups was observed. Conclusion: Leptin levels related directly to quantity of body fat tissue in fetal macrosomia as there is leptinresistence causing elevated leptin evels.

DOI

10.21608/jhiph.2013.19990

Keywords

leptin, Macrosomia

Authors

First Name

Manal

Last Name

Swelem

MiddleName

-

Affiliation

Department of Obstetrics & Gynecology, El-Shatby University Hospital, Alexandria, Egypt

Email

-

City

-

Orcid

-

First Name

Yasser

Last Name

Elkassar

MiddleName

-

Affiliation

Department of Obstetrics & Gynecology, El-Shatby University Hospital, Alexandria, Egypt

Email

-

City

-

Orcid

-

First Name

Abd Elmoneim

Last Name

Fawzy

MiddleName

-

Affiliation

Department of Obstetrics & Gynecology, El-Shatby University Hospital, Alexandria, Egypt

Email

-

City

-

Orcid

-

First Name

Ahmed

Last Name

Abd Elatty

MiddleName

-

Affiliation

Department of Obstetrics & Gynecology, El-Shatby University Hospital, Alexandria, Egypt

Email

-

City

-

Orcid

-

First Name

Akram

Last Name

Deghady

MiddleName

-

Affiliation

Department of clinical and chemical pathology Alexandria University, Alexandria, Egypt

Email

-

City

-

Orcid

-

Volume

43

Article Issue

1

Related Issue

4038

Issue Date

2013-04-01

Receive Date

2018-11-28

Publish Date

2013-04-01

Page Start

75

Page End

82

Print ISSN

2357-0601

Online ISSN

2357-061X

Article File

JHIPH_Volume 43_Issue 1_Pages 75-82.pdf

PDF . 57.9kB

Link

https://jhiphalexu.journals.ekb.eg/article_19990.html

Detail API

https://jhiphalexu.journals.ekb.eg/service?article_code=19990

Order

7

Type

Original Article

Type Code

511

Publication Type

Journal

Publication Title

Journal of High Institute of Public Health

Publication Link

https://jhiphalexu.journals.ekb.eg/

MainTitle

Maternal and Fetal Leptin Level Correlation with Fetal Macrosomia

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Type

Article

Created At

22 Jan 2023