The biomodulation effect of diode LASER 940 on marginal bone loss (MBL) around implants supporting mandibular hybrid
prosthesis in controlled diabetic patients was evaluated . Twenty completely edentulous patients with moderately controlled
diabetes mellitus (DM) (glycated hemoglobin (A1c [HbA1c] =8.1%–10.0 %) were selected to participate in this study. All
patients received upper and lower complete dentures. Four mandibular straight implants were inserted in all patients then
patients were divided randomly into control group (CG) and Laser group (LG) . In LG diode LASER biomodulation with
940nm wavelength with energy 30J and 60 sec was applied around each implant. Both groups were immediately loaded with
acrylic interim hybrid prosthesis after modifying complete lower denture . Interim prosthesis used during the follow-up period
till full patient satisfaction was achieved then a definitive porcelain fused to metal hybrid prosthesis was fabricated. MBL was
measured using digital periapical radiographs with standardized long cone paralleling technique at implant loading (0 months
or baseline), 6 and 12 months. MBL was calculated at T1 (06- months), T6 (612- months) and T12 (012- months) follow-up
periods.
LG showed statistically significant lower marginal bone loss MBL than the CG at T1 and no statistically significant difference
in MBL at T6 and T12 follow-up periods. Within the limits of this study, low-level LASER biomodulation ( LLLB) may
significantly decrease the MBL around immediately loaded implants supporting mandibular hybrid prosthesis in controlled
diabetic patients at (T1) but has no effect on MBL in the subsequent (T6 and T12) follow-up periods