Desert Research Center (DRC) is one of the oldest scientific institutions dedicated to the study of the desert environment. DRC has got many specializations distributed in four research divisions, comprising 23 scientific departments that are further divided into 45 research units for the fine scientific specialties. In addition to the presence of 10 regional research stations distributed in the desert governorates of Egypt, including a station on the northwest coast, a station in Siwa Oasis, Shalatin, Toshki, New Valley, five stations in the Sinai Peninsula and to the Center for Sustainable Development of Matrouh Resources. Desert Research Centre aims to explore the natural resources in the Egyptian desert, and to develop plans to invest these resources to achieve sustainable development in order to preserve the rights of future generations This bibliography was compiled in order to shed the light on the role of DRC in the science of microbiology in Egypt since 1950.