Octopus is an important resource for the fisheries sector and has commercial value. For this reason, maintenance and conservation is requisite to preserve and keeping its survival. So, some morphometric relationships of Amphioctopus aegina was studied at the Gulf of Suez – Northern Red Sea. The results showed that the length-weight relationship of dorsal mantle length (DML) with total weight (TW) of A. aegina is negative allometric and obtained by the formula Y= 0.5198X^2.6696 with the correlation coefficient of r²= 0.8998 for males and Y= 0.8065X^2.4042 with the correlation coefficient of r²=0.9319 for females. The results indicated that 90% or more of weight gain occurs due to the old growth of the octopus body, while 10% or less of weight gain is affected by other factors such as environmental conditions and age factors. The length-length relationships of DML with the different body measurements of A. aegina showed a negative allometric (b<1). While, the relations of DML with long arm length (LAL), total length (TL) and short arm length (SAL) were positive allometric growth (b>1) for males and females and the correlation coefficient (r²) showed a good fitted data for all relationships.