The inorganic chemical composition of atmospheric Total Suspended Particulate (TSP) and Particulate Matter with an aerodynadic diameter less than 10 µm (PM₁₀) in different regions of Cairo, in spring and autumn of 2018 was illustrated in this work. The results showed that the highest concentration of TSP and PM₁₀ were close to industrial and heavy traffic areas “Tabbin, Helwan, Shobra Elkhimah and Fifth Settlement area". The results showed that dust mass concentrations in Shobra Elkhimah were higher than all the other locations in both TSP and PM₁₀. These results were pointed out in both spring and autumn. The results showed that the concentration of heavy metals in Helwan area was higher than all other locations. These concentrations suggest that heavy metals pollution in Helwan was more serious. Ration analysis of soluble ions showed that sodium and chloride were not from sea salt but sodium might be from the resuspension of soil dust, and chloride might be associated with the activities of burning. Potassium had diversity of sources other than burning of biomass. Sulfate and nitrate were mostly from fossil fuel origin. The 16NO3-"> / 16SO4-">  ratios in Tabbin were higher than in Helwan and Shobra Elkhimah for two types of particles during spring and autumn, indicating that the contribution of stationary emission to total particles in Tabbin were higher than in Helwan and Shobra Elkhimah.