The aim of this study is to prepare an applied model for the study of the effect of the economics of vaccine production on health and environment in Egypt, which will achieve the greatest benefit for individuals from the availability of serums and vaccines and the ease of immunization process that provides protection For the individuals. Which impede the production of serums, vaccines and immunization in Egypt . These challenges are the presence of some misconceptions and the lack of awareness of some individuals in the community of the benefits of serums, vaccines and the benefits of immunization in reducing diseases and eradicating them in the beginning before they spread and turn into an epidemic. Destroyed The study examined the concept of serums, vaccines and the difference between each of them in order to know the impact of these challenges on the production of vaccines, immunization and immunization process, and the impact of the immunization process in improving the health of individuals and reducing the spread of diseases and reduce the cases of infections. The study was also based on the analytical method in the practical side based on the answers of the sample of the study and on the study data which was obtained through the survey questionnaire which was distributed to the personnel working in the Holding Company for Biologics and Vaccines (275) 261). The valid questionnaire for the analysis is (250) questionnaire. The survey form is the tool used to achieve the objectives of the study by means of the statistical test of the tests using the statistical program SPSS The study found that there is a statistically significant trend in the economics of serums production and vaccines in Egypt at a significant level of 0.05. There is a statistically significant effect of the production of serums and vaccines on the status of serums and vaccines in health and environment in Egypt at a significant level of 0.05 There is a statistically significant effect for the economics of serums production and vaccines on the status of serums and vaccines in the health and environment in Egypt at a significant level 0.05