Acrylamide is a probable carcinogen and has also been shown to be a neurotoxic agent in animals and humans. This work aims at removing acrylamide from aqueous solution using potassium permanganate. Several jar tests were carried out to investigate the effect of experimental parameters including initial solution pH, dose and contact time upon the removal process. Data revealed a good percentage of acrylamide removal by potassium permanganate from 13.40% to 41.40% by increasing the dose from 0.2 to 1 ppm, respectively in neutral medium and from 29.52% to 96.67% in acidic medium. While in basic medium absence of acrylamide due to hydrolysis transformation into acrylic acid. On the other hand, results indicate a percentage of acrylamide removal from 32.96% to 54.64% by increasing the contact time from 5 to 160 minutes using 1 ppm permanganate dose in neutral. Also acrylamide removal percentage increased in acidic medium from 87.33% to 100.00% by increasing the contact time 5 to 160 minutes. The same hydrolysis transformation carried out for acrylamide in basic medium.