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25117

ESTIMATION OF ITERLEUKIN-8 AS A BIOMARKER OF AIR POLUTION IN BRONCHIAL LAVAGE OF ASTHMATIC PATIENTS

Article

Last updated: 22 Jan 2023

Subjects

-

Tags

Medicine

Abstract

Bronchial asthma is regarded as an allergic inflammation of the airways. Air pollutants have been shown to enhance allergic responses and previous studies have demonstrated that air pollutant stimulate airway epithelial cells to produce various cytokines including inerleukin-8. Broncho alveolar lavage will be done to asthmatic patients to assess the level of interleukin 8 as a biomarker of air pollution trying to find a correlation between the level of the interleukin 8 and the spirometric parameters of the study group. There is a correlation between the level of interleukin-8 and the decreased FEV1 and FEV1/FVC parameter of the study group. The more the increase in the level of the interleukin-8 the less the value of FEV1 FEV1/FVC measured for the study group. There was a significant negative relation of between the levels of IL-8 and the FEV1 were the p value was 0.006. There was a significant negative relation between the levels of IL-8 and the values of FEV1/FVC were the P values was 0.000. Air pollution is an exacerbating factor for asthma as detected by increased level of its biomarker (interleukin-8) in the lavage of the asthmatics.  

DOI

10.21608/jes.2016.25117

Keywords

Asthma, pollution, Interleukin-8

Authors

First Name

Elboukhari,

Last Name

M. S

MiddleName

-

Affiliation

Institute of Environmental Studies and Research, Ain Shams University

Email

-

City

-

Orcid

-

First Name

Kamal,

Last Name

Howaida, M

MiddleName

-

Affiliation

Faculty of Medicine, Banha University

Email

-

City

-

Orcid

-

First Name

Seoudi, M.

Last Name

M. M

MiddleName

-

Affiliation

National Institute for Chest Diseases, Embaba,

Email

-

City

-

Orcid

-

Volume

33

Article Issue

1

Related Issue

4597

Issue Date

2016-06-01

Receive Date

2016-06-17

Publish Date

2016-06-17

Page Start

145

Page End

159

Print ISSN

1110-0826

Online ISSN

2636-3178

Link

https://jes.journals.ekb.eg/article_25117.html

Detail API

https://jes.journals.ekb.eg/service?article_code=25117

Order

8

Type

Review Article

Type Code

599

Publication Type

Journal

Publication Title

Journal of Environmental Science

Publication Link

https://jes.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023