The current study aimed at investigating the effectiveness of using the flipped learning model in developing EFL reading comprehension and self-regulated learning skills among EFL General Diploma in Education students. The participants were forty students. They represented one experimental group. Three main instruments were used for data collection: reading comprehension skills checklist, reading comprehension skills test and self-regulated learning skills scale. The students were taught using a proposed strategy based on flipped learning for twelve weeks. Data collected through the pre- and post-administration of the instruments was subjected to t-test. The results revealed through the post-administration of the reading comprehension test and the self-regulated learning scale displayed that the post-performance of the students significantly exceeded their pre-performance. Therefore, the results reflected support for the four study hypotheses. They proved the positive effect of the strategy on developing EFL reading comprehension and self-regulated learning skills among EFL General Diploma in Education students.