The current experiment aimed to estimate some antioxidants ability mainly, selenium, vitamins B₆ and C to overcome adverse effect of heat stress during summer months. Total of 360 one- day-old broiler chicks were randomly divided into 9 treatments with four replicates (10 chicks/each). The experiment period extended from 1 day to 40 days of age where ambient temperature ranged from 36 to 41°C and relative humidity ranged from 30 to 55%. The 1^st group fed basal diet that satisfied strain requirement as control treatment. The 2^nd group fed control basal diet supplemented with vitamin E (50 mg/kg diet) and acted as control plus to estimate efficiency of antioxidants. Experimental treatments from the 3^rd to the 9^th fed basal diet supplemented with 3 mg vitamin B₆, 200mg vitamin C, 0.10 mg Se, 3 mg vitamin B₆+ 200mg vitamin C, 3 mg vitamin B₆ + 0.10 mg Se, 200 mg vitamin C + 0.10 mg Se, or 3 mg vitamin B₆ +200mg vitamin C+ 0.10 mg Se respectively.. Parameters of growth performance, carcass characteristics, some plasma constituents, immunity and antioxidant status were investigated. Malondialdehyde was estimated in frozen (6 months at -20 °C) thigh muscles to determine antioxidant status. The results appeared significant improvement of growth performance and malondialdehyde were reduced in plasma and thigh muscles. Dressing, abdominal fat and giblets percentages did not affect. While, significant improvement was observed in some hematological parameters, cellular immunity and antioxidant status. In contrast antibodies titer against Newcastle Disease Virus and Avian flow Virus (H5N1) did not affect. Briefly, the overall experimental results showed that supplementing broiler diets with selenium combined with vitamin B₆, vitamin C or both were more effective to improve growth performance, broiler meat quality, immunological and antioxidant status for broiler chicks reared  during hot summer months.