The aim of this study was to determine the effectiveness of the use of curcumin-containing turmeric powder (TP) and hydrated sodium calcium aluminosilicate (HSCAS) alone or in combination to alleviated aflatoxicosis in broiler chicks. A total of 480 day-old broiler chicks were separated into 8 treatments. Each of the 8 dietary groups was divided into four replicates of 15 chicks each. The first group was fed basal diet and used as control. The other treatments (from 2 to 8 ) were fed the same basal diet and supplied with 0.5% turmeric powder (TP) including 1.48% total curcuminoids (80 mg/kg (80 mg/kg), Hydrated sodium calcium aluminosilicate (HSCAS) alone (0.5% ), TP (0.5%) plus HSCAS (0.5%), Aflatoxin B1 ( AFB1) alone in the diet (1 mg/kg of diet), AFB1 plus TP (0.5%), AFB1 plus HSCAS (0.5%) and AFB1 plus TP (0.5%) plus HSCAS (0.5%, respectively) for 35 day. The findings showed that the turmeric or HSCAS substantially addition to the AFB1 diet increased feed consumption and body weight and decreased liver weight. Supplementation of turmeric or HSCAS and turmeric with HSCAS reinforced the harmful effects of AFB1 on serum constituents. Furthermore, decreased antioxidant functions and increased serum and liver homogeneous malondialdehyde (MDA) concentrations due to AFB1. In conclusion, the combined method to the management of aflatoxicosis in broiler chicks can be considered to be the addition of HSCAS and/or turmeric